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一次通用型局麻药FET 传感器的研制与应用
摘要:报道了一种用四苯硼钠作为电活性物质, 邻苯二甲酸二辛酯作为增塑剂的通用型局麻药( 普鲁卡因、丁卡因、 利多卡因) 场效应晶体管传感器( 局麻药FET) . 该传感器全固态化, 体积小, 易微型化, 集成化和多功能化. 利用半导 体工艺可以批量生产, 价格便宜, 可作为一次性使用. 用传感器分析局麻药品注射液的含量, 结果和药典方法相一 致.
关键词:  离子敏感场效应晶体管  四苯硼钠  普鲁卡因  丁卡因  利多卡因  药物分析
Development and Application ofOne􀀁time Polyfunction Local Anaesthetic FET
Abstract:This paper describes a kind of local anaesthet ic sensitive field effect transistor sensors for procaine, dicaine and lidocaine with tetraphenylborate as electric active material, dioctyl phthalate as plosticizer. It is a solid??state, small size, miniatured, integrated, fast response and low output impedance. The sensor has not only the feature of ISFET but makes facilities and low??priced. So it is possible to be used for one??time. It can be used to analyse the contents of local anaesthet ic drug in injection, and the result agrees with the method in pharmacopoeia of China.
Key words:  ion sensitive field effect transistor  tetraphenylborate  procaine  dicaine  lidocaine  drug analysis

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